09-P036 Orthodenticle controls timely photoreceptor development in Drosophila
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چکیده
منابع مشابه
09-P036 Orthodenticle controls timely photoreceptor development in Drosophila
right ventricle and the outflow tract of the heart. Here we have investigated the role of tailup (tup), the Drosophila homologue of vertebrate islet-1 in the development of the dorsal vessel. In Drosophila, cardiac progenitor cells are specified bilaterally in the dorsal mesoderm, which requires complex interactions between the transcription factors Tinman/Nkx2.5, Pannier/GATA factor, and Dorso...
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Neurons present a wide variety of morphologies that are associated with their specialized functions. However, to date very few pathways and factors regulating neuronal maturation, including morphogenesis, have been identified. To address this issue we make use here of the genetically amenable developing fly photoreceptor (PR). Whereas this sensory neuron is specified early during retinal develo...
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The homeobox gene orthodenticle (otd) specifies anterior head development in the Drosophila embryo, otd-related genes are also found in vertebrates, with expression patterns suggesting that they are important for the development of anterior regions of the head and brain. Here, we analyze the molecular mechanisms by which otd expression is activated within its normal domain in the head and repre...
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The adult head capsule of Drosophila forms primarily from the eye-antennal imaginal discs. Here, we demonstrate that the head primordium is patterned differently from the discs which give rise to the appendages. We show that the segment polarity genes hedgehog and wingless specify the identities of specific regions of the head capsule. During eye-antennal disc development, hedgehog and wingless...
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The liver forms as part of digestive system. Despite the essential functions of the liver, little is known about its early embryonic development. The clamped s819 mutant was identified in a forward genetic screen for mutations causing defects in endodermal organogenesis in zebrafish. At 44 h post-fertilisation (hpf), clamped s819 mutant embryos display liver hypoplasia and defects in extrahepat...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2009
ISSN: 0925-4773
DOI: 10.1016/j.mod.2009.06.366